Medicated Gum
Patient Benefits
Faster onset of action allows for a more pleasurable experience than taking tablets:
- readily available
- no need for water
- discreet
- pleasant taste
Easy to remove from the mouth if a nausea episode is experienced and can be easily replaced for remaining dosage benefits.
- Novel drug delivery format
- Low tack formulation
Opportunites
Anti-migrane drugs - providing rapid delivery of an API via the buccal mucosa, bypassing gastric absorption and reducing the impact of gastric stasis
Anti-emetics - as a preventative for chemotherapy induced nausea and vomiting (CINV) or post-operative induced nausea and vomiting (PONV), particularly suitable with older children and young adults
Analgesics - such as ibuprofen, aspirin, naproxen etc.
Existing Applications - improving release characteristics and taste of existing gum formulations
OTC applications - particularly suitable for transition from ethical to OTC applications
Mucoadhesives - Opportunity to collaborate with Revolymer TM for many other applications eg mucoadhesive technology
Stage in development
The chart above demonstrates how the release profile of ibuprofen from a chewing gum is substantially improved when one of Revolymer?s proprietary polymers is included in the formulation.